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Goal: to summarize the mechanisms and clinical implications

103108 In isolated rat small intestine, the capacity for permeability of the upper part of the villi is generally lower than that of the lower part and the crypt is highly permeable to molecules with radii of up to 60
Ignoring reconstitution volume in dose calculations

Mitochondria, as the primary site of ROS production, are often subjected to high levels of ROS, leading to oxidative damage of mitochondrial DNA