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In well-controlled studies assessing CVD risk using multivariate approaches to adjust for covariates, both apoA-I and HDL-C are strong independent predictors of CVD risk (474)

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An agent comprising an oligo- or poly- nucleotide may be any one of a DNA vaccine, an antisense oligonucleotide, a ribozyme, a catalytic DNA (DNAzyme) or RNA molecule, an siRNA or an expression construct encoding therefor