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Ann Thorac Surg 113(4):1399-1400, 2022

Sanofi.ca (2017)

reported reduced expression of genes responsible for melanin synthesis in the hair folliclesuch as TYR, melan-A (MLANA), premelanosome protein (PMEL), TYRP1, SLC45A2, KIT, G proteincoupled receptor 143 (GPR143), and OCA2in patients with premature graying.15 UV radiation UV radiation plays an important role in hair graying by stimulating the production of free radicals

SAH level was correlated with methyltransferase inhibition and cognitive impairment in PD and AD patients (Kennedy et al
