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This formation typically occurs at complexes I and III of the ETC [3]
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Different epidemiological studies have shown a correlation between the exposure of these substances (especially in the case of pesticides) and appearance of PD [14-15, 17, 53]

In addition to diet control, the existing standard treatment mainly includes the use of aminosalicylic acids, glucocorticoids, immunosuppressors, and biologics (Niu et al., 2021)

There are now hundreds of papers that deal with the detoxifying capacity of SF, and there are well over a thousand studies focused on Nrf2 from a detoxication perspective
