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Likewise, corneal neovascularization might be induced by hypoxic conditions (upregulation of proangiogenic factors, downregulation of anti-anxiogenic factors to supply oxygen to the cornea) [181]

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Auranofin treatment alone was sufficient to induce a modest level of ER stress, seen in upregulation of UPR target genes in the absence of any other ER stress stimulus (Figure 3E)