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Their presence and activity in the human body may disrupt normal hormonal balance, leading to various health problems [167,168,169] (Figure 5)

doi: 10.1007/978-1-4615-1833-4_18

Tan DJH, Wong C, Ng CH, Poh CW, Jain SR, Huang DQ et al (2021) A Meta-Analysis on the Rate of Hepatocellular Carcinoma Recurrence after Liver Transplant and Associations to Etiology, Alpha-Fetoprotein, Income and Ethnicity

This confirms the ability of these prodrugs to induce intrinsic apoptotic cell death

The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats