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Description
GSH-activated prodrugs, including disulfide- and diselenide-linked conjugates, are selectively activated in tumors, enabling high drug loading and targeted delivery

However, it is likely that even after dealkylation the degradation product of NMY1009 retains at least some uncoupling activity

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It is traditionally associated with diseases categorised as autoimmune that involve the adaptive immune system mistakenly recognising the body's own molecules as foreign and mounting an immune response against them

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