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Results are presented as meansSEM (in figures), meansSD for normally distributed data, or median with IQR (first to third quartile) for log normally distributed variables (in ESM tables), and compared by mixed-model repeated-measures ANOVA (mixed-model ANOVA) adjusted for BMI and age, and with TukeyKramer correction

A deficiency of omega-3 fatty acids can significantly increase the risk of developing anxiety disorders

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It is crucial to follow the dosage recommendations provided by a healthcare professional and monitor for any adverse effects

Preparation of MSU 1 g UA was dissolved in 200 mL DI water containing 6 mL sodium hydroxide (NaOH, 1M) at 70 C