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1 Narcolepsy is a chronic hypothalamic neurodegenerative disorder and a quite disabling condition, presenting with several sleep-wake cycle related symptoms, such as excessive sleepiness (ES) and dissociative manifestations of REM sleep, such as cataplexy, sleep paralysis, hypnagogic hallucinations, and early REM sleep (REM sleep naps, SOREMP) 2

doi: 10.1016/j.jpsychires.2014.02.005

S-layer extract was then filtered and resolved onto a Superdex 200 26/600 column using an KTA Pure FPLC system (GE Healthcare) in 10 mM Tris-HCl pH 7.5, 100 mM NaCl, 5 mM EGTA buffer

We did not detect a difference between behavior of wild type and lite-1;gru-3 double mutant animals at 30 min and only a small difference (p-value=0.04) at 1 hour (Fig

[DOI] [PubMed] [Google Scholar] 20.Olzmann JA, Carvalho P