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74 Under stress, AMPK activation triggers the translocation of MOTS-c to the nucleus, where it binds to nuclear DNA and interacts with transcription factors such as NRF2 and ATF1, modulating nuclear gene expression to restore cellular metabolic homeostasis

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A

Maintain more stable internal levels

We applied L-NAME (5 mg/kg), L-arginine (100 mg/kg) alone or combined, intraperitoneally, at 30 minutes before amputation

Stimulation of collagen synthesis: GHK-Cu directly activates dermal fibroblasts, the cells responsible for collagen production