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DGK overexpression leads to defects in TCR signaling, while its deficiency promotes T cell expansion and IL-2 secretion

Materials and Methods Chemicals and standards LC grade solvents and common chemicals (ACS grade) were purchased from Sigma-Aldrich (Munich, Germany) and Fisher Scientific (Schwerte, Germany)

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Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogenactivated protein kinases involves transactivation of cKIT
