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World J Gastrointest Pathophysiol

Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

[Google Scholar] 41.Zller B., Li X., Sundquist J., Sundquist K

Conclusions This body of work demonstrates the development and validation of assays using a tissue chip platform for high-content drug screening and the successful discovery and in vivo validation of candidate radioprotective drugs with non-antioxidant primary modes of action

Production of Astaxanthin and 4-Ketozeaxanthin by the Marine Bacterium, Agrobacterium Aurantiacum