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Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration

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Argani P, Lal P, Hutchinson B, Lui MY, Reuter VE, Ladanyi M

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We revealed that DAF-16 activation is an important factor that mediates the extended lifespan of the glp-1(-) and fem-3(-) mutants, and its forced activation can reverse the shortened lifespan of the mog-3(-) mutant