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18 Overall, ALC was generally well tolerated, with predominantly mild GI and CNS events, and no evidence of excess serious AEs compared with controls

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Noteworthy, analyzing results according to baseline vasculogenic ED degree category, at study completion, IIEF-6 score was significantly increased in both subgroups of patients with mildmoderate and severe vasculogenic ED, whereas PSV was significantly increased only in the subgroup of patients with mildmoderate vasculogenic ED, despite a significantly lower baseline PSV in l-ARG compared to placebo group

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Two agonists on the same receptor amplify these without a matching efficacy gain
