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The pathogens energy metabolism is also reconfigured, with the cytochrome bd oxidase becoming essential for maintaining respiration under acidic stress in activated macrophages (Lee et al., 2025)
229, 231, 237, 238 Cohort sizes ranged from 8 to 22 patients (total 70)

Similar content being viewed by others Introduction Acetaminophen (paracetamol, APAP) is safe to use at therapeutic doses, but can cause acute liver injury (ALI) when overdosed

Informed written consent was obtained from all participants or, if participants are under 18, from a parent and/or legal guardian

[DOI] [PubMed] [Google Scholar] 82.Pienta K.J., Nailk H., Akhtar A., Yamazaki K., Replogle T.S., Lehr J., Donat T.L., Tait L., Hogan V., Raz A