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Moreover, besides the enhanced activity of fibroblasts, which are considered essential for collagen synthesis, tissue repair, and regeneration, there was also a potential rise in mast cell activation

While the CRISPR Therapeutics research is farther along, all of this research is early-stage
doi: 10.1038/190923a0

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Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II
