glutathione peroxidase kit Invitrogen™ (GSH-Px) Activity The oxidised glutathione formed is recycled by glutathione reductase and NADPH Solarbio Glutathione Peroxidase (GSH-Px/GPX) Activity

The primary mechanical injury in TBI triggers secondary injury cascades involving neuroinflammation, oxidative stress, mitochondrial dysfunction, and excitotoxicity

References 1.Majumder A

3.3.2 MGBA and anxiety disorders Emerging evidence highlights the MGBA as a critical contributor to anxiety pathophysiology ( NCAM1, CADM2 , and PHF2/FAM120A also correlate with anxiety and mood disorders ( Bifidobacterium taxa appear protective, while Lactobacillaceae increase anxiety risk (Lai and Xiong, 2025)

Acute respiratory response to traffic-related air pollution during physical activity performance

We have addressed the suggestions to the best of our ability and summarize the changes below, along with the original comments from the reviewers