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37 However, peptides derived from mammalian tissues and synthetic sources often encounter pharmacokinetic limitations, including rapid degradation, short plasma half-life, and poor oral bioavailability

269 XiaoA.ZhangY.RenY.ChenR.LiT.YouC.et al (2021)

Some of these compounds have promising therapeutic effects in animal models and in several clinical trials for various pathologies including chronic neurological diseases

Cytotechnology 72(1):8195

D-2 but not D-1 dopamine agonists produce augmented behavioral response in rats after subchronic treatment with methamphetamine or cocaine