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Mitochondrial DNA (mtDNA), which encodes 13 essential subunits of the electron transport chain (ETC), is particularly susceptible to oxidative stress, resulting in replication errors, point mutations, and large-scale deletions (Robichaux et al., 2023)

Specifically, the physicochemical and biological mechanisms through which nanoencapsulation enhances the stability, solubility, bioavailability, and targeted delivery of bioactive compounds (shown in Figure 2) are explored, as understanding these mechanisms is essential for translating engineering innovations into effective, evidence-based nutritional interventions

A good review of the pathophysiology of COPD

Kohli R, Meininger CJ, Haynes TE, Yan W, Self JT, Wu G (2004) Dietary l-arginine supplementation enhances endothelial nitric oxide synthesis in streptozotocin-induced diabetic rats

mature virus particles then infect other cells, initiating a new virus lifecycle and further expanding the scope of infection [5]