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A more recent retrospective, case-controlled study found a survival benefit in patients with ALS taking 1.5 g/day of acetyl-L-carnitine, but not for patients taking 3 g/day

Merighi A, Salio C, Ferrini F, Lossi L

[DOI] [PubMed] [Google Scholar] 83.Kohrogi R., Shimamoto S., Nakashima K., Sonoda D., Ohtsuka A., Ijiri D

This indicates that the build up of A intraneuronally is an indicator of early events in AD pathogenesis

Zebrafish and mouse husbandry and treatment Zebrafish wild type (WT) lines used in this work, including those used for the generation of the stable mutant lines, derived from Tuebingen and Giotto strains matings
