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Acknowledgements This work has been supported by the NIH/NIA grants: R01AG056478, R01AG055865, and AG056478-04S1 (M.K.H.), R01AG075998 (M.K.H
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and asparagus, nuts and seeds such as walnuts, pumpkin seeds and chia seeds
PDK can decrease PDHC activity through the phosphorylation of PDHE1 on Ser293, Ser300, and Ser232, thereby inhibiting the TCA cycle and resulting in the accumulation of pyruvate and the production of lactic acid
Proper storage is essential to maintain the integrity of BPC-157
