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In that pathological model, plasma homocysteine accumulation was mainly attributed to increased homocysteine production from methionine but not impaired homocysteine conversion to cysteine
Levels decline with age and stress, which is why medically supervised supplementation can be beneficial for some patients
Vincze, A., Mazlo, M., Seress, L., Komoly, S
References 208 and 209 identify a stress response that is induced by accumulation of mitochondrial precursor proteins in the cytosol
