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Remove the culture medium and add Adipogenic Induction Medium A

Mitogen Activated Protein Kinase (MAPK) Activation, p53, and Autophagy Inhibition Characterize the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein Induced Neurotoxicity

This activation stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and most significantly for weight management, reduces appetite through effects on hypothalamic appetite centers

Weinberg et al., 2019

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