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In the last decade, studies on the condition of BBB in neurodegenerative diseases, including ALS, have demonstrated the presence of vascular disruption, a condition that could theoretically favour the entry of drugs into brain regions affected by neurodegeneration
10.1016/S0083-6729(05)72005-7 88 MorelM.MeuxE.MathieuY.ThuillierA.ChibaniK.HarvengtL.et al
If you notice any discomfort, try taking them with a small amount of food or reducing the dose while your body adjusts
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