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Identification and characterization of Cardiac Glycosides as senolytic compounds
doi: 10.1093/toxres/tfaa079

Inhibition of cco-1 is a well-known intervention that, similarly to mrps-5 RNAi, activates the UPR mt and extends lifespan in worms 21

Among them, neutrophils are the most abundant and are essential for detecting pathogens and initiating immune cascades through processes such as swarming, cytokine production, degranulation, phagocytosis, and the formation of neutrophil extracellular traps (NET) (89, 90)

doi: 10.1111/j.1600-079X.2005.00242.x, 150
