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Specifically, TfR1, GPX4, SLC7A11, SLC3A2 and SLC40A1 were significantly downregulated, while FTH/L, ACSL4, HO-1, NCOA4 and LC3II were upregulated (Fig

The function of mitochondria also plays a vital role in cell health, intercellular communication, regulated cell death, and cell growth

This signaling, even when mediated through the same pathways, can have different spatial and temporal localization and is associated with distinct consequences [106]

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GSTP1 was identified as a palmitoylated protein after 8 h of metabolic labelling with -alkynyl-palmitate, while palmitoylation of other proteins (e.g., N-Ras) is very rapid (less than 1 h) and standard protocols are 4 h [45]