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In states of chronic GI inflammation, this mucus layer is often degraded, leaving the enterocytes exposed to harsh digestive enzymes and pathogenic bacteria
[DOI] [PubMed] [Google Scholar] 50.Lu Y., Zhang L., Wang C., Gong C
pmid:23076896 21

The alternate arrangement of the R-domain in the 7MPE model is physically plausible as it places a cluster of electronegative side chains where our model has placed phosphates

doi: 10.3390/antiox10091479 165 TangM