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Transient glutathione depletion in the substantia nigra compacta is associated with neuroinflammation in rats

[91] Since only bacteria and some archea possess the genes and enzymes necessary to synthesize vitamin B 12 , plant and algae sources all obtain the vitamin secondarily from symbiosis with various species of bacteria, [5] or in the case of fermented plant foods, from bacterial fermentation

These metabolic switches should influence astrocyte functions such as energy supply, redox balance, and inflammatory responses, thereby contributing to disease progression (Figure 4)

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Por su contenido de Tiamina, se puede presentar enrojecimiento en cara, nusea, vmito, rash y diarrea que son transitorios y no obligan a suspender el medicamento