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Description
The immune privilege is maintained by the expression of Fas ligand (FasL) on the surface of disc cells, which induces apoptosis in cells carrying the Fas receptor
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Activated autoreactive T-cells such as Th1 cells from secondary lymphoid organs (i.e., spleen or pancreatic lymph nodes) infiltrate into the pancreas and cause -cell destruction
, Reference Hedderich2022
