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Ferroptosis, a form of regulated cell death initiated by lipid peroxidation, differs from other types of cell deaths at genetic, biochemical, and morphological levels 24,25

30 Catalase catalyzes the disintegration of hydrogen peroxide

Although it is primarily known as a genotoxic biomarker and a potential non-invasive serum indicator for patients with non-small-cell lung cancer and breast cancer 87 , elevated levels hold strong clinical relevance, especially in triple-negative breast cancer (TNBC), where baseline levels are comparatively low 88

Molecular analysis covering mutation hotspots and gene fusions/gene skipping was carried out with either Ion AmpliSeq TM V2 Lung/Colon cancer panel (Thermo) or Archer Fusion Plex Lung Panel (ArcherDX) or by using targeted Idylla BRAF, KRAS and EGFR mutation kits (Biocartis)

More High glucose increased ROS (reactive oxygen species) generation in endothelial cells