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Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases

This research was enabled in part by support provided by Calcul Qubec and Compute Canada (www.computecanada.ca)

Nanoparticle-delivered siRNA targeting Brutons tyrosine kinase for rheumatoid arthritis therapy

Reduced PPI is believed to be the result of deficits in the neuronal circuitry involved in sensorimotor gating, a pre-attentive brain function that facilitates the integration of motor and sensory stimuli

These include increased concentrations of PUFAs, increased concentrations of PEs, increased concentration of lipid peroxides, and longer acyl tails