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Treatment of Pernicious Anaemia Key Points in the treatment of PA Treatment of cobalamin deficiency is recommended in line with the British National Formulary: By intramuscular injection: With neurological involvement* : Initially 1 mg once daily on alternate days until no further improvement, then 1 mg every 2 months

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When B12 levels are low, red blood cells can become large and inefficient, contributing to fatigue and weakness
