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In addition, DC membranes can activate antigen-presenting cells and deliver peptide antigens, enabling the activation and maintenance of antigen-specific T cells, which in combination with immune checkpoint inhibitors can achieve more sensitive and durable antitumor immunity

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LDN also quiets overactive immune cells in the brain and spinal cord (called microglia) that drive inflammatory responses in conditions related to immune system and persistent pain think of it as finally silencing a car alarm that's been going off for months

doi:10.1007/s10815-021-02247-5