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In this episode of the Modern Thyroid and Wellness Podcast, host McCall McPherson sits down with Jeff Moshal, CEO of Genus Lifesciences Inc., for an in-depth discussion about the critical state of natural desiccated thyroid (NDT) medications, including their flagship product Ren Thyroid

Beyond that, based on previous assumptions, lactate was surprisingly discovered to exhibit inhibitory effects on wild GPR81(-) macrophage cell lines, which included abrogating LPS-induced IL-6 expression depending on concentration

In BRAF-mutant melanoma, DTP cells emerging after MAPK inhibitor treatment demonstrate increased intracellular calcium signaling via P2X7-mediated ERK reactivation, which supports survival in the drug-tolerant idling state (Stauffer et al., 2024)

We next assessed respiration in response to distinct substrates that feed into CI via NADH generation from glycolysis, beta oxidation and glutaminolysis