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[DOI] [PubMed] [Google Scholar] 72.Li L, Ameri AH, Wang S, Jansson KH, Casey OM, Yang Q, et al

In addition, gamma-glutamyl transferase (GGT) levels exhibit a negative association with cognitive performance, while elevated alkaline phosphatase (ALP) levels increase the risk of A deposition, PET burden, and cognitive impairment [60]

RNS forms lipid peroxides in plasma membranes and intracellular organelles [143]

Figure 3-2 illustrates the relationship between a quantal dose-response curve for the therapeutic effect of a drug to generate a median effective dose (ED 50 ), the concentration of drug at which 50% of the population will have the desired response, and a quantal dose-response curve for lethality by the same agent

Immunomodulatory therapies These interventions aim to restore immune tolerance, reduce autoimmune attack, or protect beta cells without direct genetic modification