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While KRAS and BRAF mutations are certainly two of the most frequently mutated oncogenes in human cancer, they are not the only mutations known to affect glucose metabolism and sensitivity towards ascorbate therapy

Glutathione binding to the Bcl-2 homology-3 domain groove: A molecular basis for Bcl-2 antioxidant function at mitochondria

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doi:10.1172/JCI59755 [PMC Full Text] [PubMed] [Crosslink] 59

971 With the help of glucose transporter 1 on the surface of the BBB, glucose-modified GluAC4A is transported into the brain, achieving targeted drug delivery across the BBB