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However, their effectiveness requires extreme adherence, and important gaps remain, particularly in the genetic dimension

In AD, NAC elevates GSH levels to sustain GPX4 activity, thereby reducing lipid peroxidation accumulation and inhibiting key ferroptosis pathways for neuroprotection (188)

N Engl J Med 366 (18): 1663-73, 2012

While results can last with ongoing care, they are not permanent

doi: 10.1038/nature08780 140 PatelS
