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Humbert GliSODin Promotes Antioxidant Defences and Protects Against Oxidative Stress It is concluded that supplementation with gliadin-combined standardized melon SOD extract (Glisodin) promoted the cellular antioxidant status and protected against oxidative stress-induced cell death The potential benets to health of antioxidant enzymes supplied either through dietary intake or supplementation is still a matter of controversy

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Furthermore, a crosstalk between insulin-induced ERK and epidermal growth factor (EGF) favored tumorigenesis by triggering the expression of anti-tumor immunity inhibitor programmed death-ligand 1 (PD-L1) in a cancer common in individuals with insulin resistance, pancreatic ductal adenocarcinoma (78)

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