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daily for 14 days using a 1-mL syringe and a 23-gauge needle

Recalcitrant acne is acne that has not responded to multiple other therapies, including antibiotics

19 Maternal vitamin B 12 deficiency has been associated with increased risk of common pregnancy complications, including spontaneous abortion, low birth weight, intrauterine growth restriction and neural tube defects

Certain gut bacteria like Bacteroides fragilis , Fusobacterium varium , and Campylobacter coli can produce biotin

The paper is Awosemo et al
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