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In a mouse xenograft model, Par-4 knockdown effectively blocked ferroptosis-mediated tumor suppression, suggesting the potential use of Par-4 for cancer therapy [129]

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If APAP levels exceed 10 mg/L or if AST/ALT are elevated, IV NAC should be initiated without delay to minimize liver damage [28]

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The authors, however, did not characterize the rats behavior in relation to the diet, but classified the pro- or antinociception property of the oxylipins based on previous literature reports