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Some stimulate brain-derived neurotrophic factor (BDNF), the protein most essential for neuronal survival and new connection formation

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Low virulence strains express ECE1 transiently when in contact with keratinocytes to synthesize this toxin

For instance, hepatocarcinoma cells express succinyl-CoA:3-oxoacid-CoA transferase (SCOT1), encoded by 3-oxoacid-CoA transferase (OXCT), which facilitates tumor growth under nutrient-deprived conditions [110]