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Res 200 , 298307 (2022)
Lichtenwalner et al., reported that altered levels of IGF-1 negatively affect neurogenesis and synaptic plasticity, particularly in the hippocampus [36]
doi: 10.1093/af/vfad052 201 LuJ.LiH.YuD.ZhaoP.LiuY
The authors also found that the 1298AC genotype, but not the 1298CC genotype, was correlated with a more severe subtype of UC [137]
But they work best when you understand what each compound does, why it does it, and how the mechanisms interact
