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In CHF model of rat treated by monocrotaline, reduced caspase-3 expression in skeletal muscle were similarly reported in response to LC administration at a dose of 50 g/kg b.w

Garcia-Cruz VM, Arias C

Therefore, it is essential to pay attention to the dietary requirement of lysine and investigate if the requirement is met through the diet when implementing lysine supplementation

The increase of plasma long-chain ACs indicated that the fatty acid oxidation of depressed rats was incomplete, which may lead to a decrease in activities ( Table 1 Main information of pre-clinical researches studying the correlation between carnitine level and depression in animal