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In response to ROS, NE leaves the azurophilic granule and translocates to the nucleus, where it initiates relaxation and decondensation of chromatin by cleaving histones, a crucial event in NET formation
Kang CM, Chiang BL, Wang LC
Am J Hum Genet 26 : 244246
HO-1 / mice were used to prove that the deletion of HO-1 would aggravate myocardial injury in ischemia/reperfusion, especially related to diabetes
Cambridge Medicine
