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It is more complicated, and there are currently no known biomarkers for the type 2-low endotype

However, although numerous aspects indicate the beneficial action of B 12 for the prevention or treatment of (sub-)clinical DPN, there are no reports in the literature unequivocally linking B 12 treatment with its beneficial effects on DPN on a molecular basis

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Differential activities of rat and human lung glutathione S-transferase isoenzymes towards benzo(a)pyrene epoxides