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An old school interpretation of ER/SERM action is the ligand dependent mechanism, when ligand binds to ER, the heat shock proteins dissociates and the two-receptor subunits dimerize

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Unconjugated bilirubin inhibits the oxidation of human low density lipoprotein better than Trolox

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Vitamins have excellent neuroprotective effects against the oxidative stress induced by metal and non-metals, and can protect against lead-induced neuronal apoptosis in rats (Ebrahimzadeh-Bideskan et al., 2016), aluminum-induced neuronal apoptosis in Nile perch (Khalil and Hussein, 2015), iron-induced oxidative stress in rat brain tissue (Ganie et al., 2014), and arsenic-related neurological damage in rats (Sarkozi et al., 2016)

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