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The actual directionality of this interaction is still not clear, however the immune response to an external pathogen could provoke unblinded oxidative stress which in turn perpetuates a steady inflammatory cascade (Maes et al
Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B
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The face, scalp, palms, soles, and genitals may also be involved, but the mucosa is invariably unaffected
