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Rosuvastatin was not mutagenic or clastogenic with or without metabolic activation in the Ames test with Salmonella typhimuriumand Escherichia coli, the mouse lymphoma assay, and the chromosomal aberration assay in Chinese hamster lung cells

The addition of -sitosterol to colon cancer cells has been reported to reduce cell membrane cholesterol levels by about 26% (80)

When oxidative stress occurs in neuronal cells, the levels of free radicals increase, and HO-1 is rapidly activated

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