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Quercetin also reduced periostin-induced eosinophil chemoattractants, such as those regulated on activation, normal T-cell expressed and secreted regulated upon activation, normal T-cell expressed and secreted (RANTES), and eotaxin from HNEpC [48]

Scientists think this is because the two drugs have a synergistic effect, i.e., they enhance each other's effect

These events lead to a state of persistent inflammation and chronic oxidative stress (8285), characterized by increased ROS production, reduced GSH peroxidase activity, selenium deficiency and reduced GSH levels (8091)

For example, at least three different human SIGLEC7 isoforms are known

Wei T, Thakur S, Liu M, Wen J