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Nicotinamide adenine dinucleotide (NAD + ) is a critical cofactor and substrate for enzymes essential in cell signaling, damage repair, and regulation of lifespan 9,10

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Special cases: In patients with neurological symptoms, the frequency may be initially more frequent and maintained at shorter intervals for a longer period of time

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The most common discharge pattern on the EEG is burst suppression, followed by high amplitude dysrhythmias and multi-spike discharges, with corresponding changes in the EEG after the patient receives PN treatment [27]